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Research and clinical experience suggest that IV NAD+ produces a sharp but short-lived spike in plasma levels that does not reliably translate to intracellular increases, which is where the therapeutic effect actually happens
E.GalvanV
It exhibits lipophilicity and possesses a high degree of diffusivity in tissues and cells (114)
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Regulation of cell physiology and pathology by protein S-glutathionylation: lessons learned from the cardiovascular system
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